Anupama's early life began in Irinjalakuda, Kerala, where she was born to E. Parameshwaran and Sunitha. Her educational journey commenced at Don Bosco Higher Secondary School, Irinjalakuda, followed by National Higher Secondary School Irinjalakuda. Currently, she is pursuing a degree in B.A. Communicative English at CMS College Kottayam.
Anupama's foray into the Malayalam film industry was marked by the super hit film Premam, which catapulted her to fame. Her portrayal of Mary in the movie earned her widespread acclaim. Prior to her film debut, she had gained some initial acting experience through her involvement in dramas.