As Commissioner Lohmann prepares for his vacation, an unexpected phone call brings him back to work. An Interpol agent has been murdered, and the head of a mysterious organization wants to establish contact with Chicago's gangster underworld. The investigation unfolds with a series of mysterious murders, all leading to a penitentiary. FBI Agent Joe Como joins the case, but Lohmann's doubts about Como's identity begin to surface. When a victim's belongings reveal a connection to Dr. Mabuse, Lohmann suspects the infamous mind behind the crimes.
The Return of Dr. Mabuse
In this thrilling tale, a cunning doctor manipulates prisoners' minds to carry out his sinister plans, but a determined team of German police, assisted by a skilled FBI agent, is hot on his heels to bring him to justice.