In 2018, Skynet has destroyed most of humanity and survivors have been hiding underground from an army of machines, known as "Terminators". After a failed attack on a Skynet base, John Connor, the man fated to lead the Resistance is the sole survivor. On the other hand, Marcus Wright, who only remembers being on death row, meets Kyle Reese and it is believed by Connor that he was sent from the future to kill him. Now Marcus and John must unlikely join forces in order to save Kyle Reese and the humans captured by the machines.