A shy comic book fan becomes a superhero after being injected with a serum that gives him spider-like abilities, but things quickly spiral out of control as he loses his judgment and starts to develop a large spider body, experience constant pain, and hunger.
Earth vs. the Spider
A timid comic book enthusiast receives an innovative serum from a lab researching ways to grant humans arachnid powers, initially manifesting in enhanced strength, enabling him to engage in intense battles.