The film tells the story of St. Francis of Assisi's life, as recounted by his followers after his death. It chronicles his transformation from a privileged youth to a beggar for others, inspiring his friends to live a life of poverty according to the Gospels. The movie follows Francis' quest for the Pope's blessing, his persecution by the family of Chiara Offreduccio, and his struggles with his own order. Despite setbacks and illness, Francis finds solace in a message from the Lord and dies with a smile.