Dr. John Becker, a misanthropic doctor, runs a clinic in New York City, assisted by Margaret Wyborn and Linda, who is less skilled but kept on due to Becker's tolerance. His best friend is Jake Malinak, a blind newsstand owner across the street from the diner. The diner, previously run by Reggie Kostas, is now managed by Chris Conner, whom Becker simultaneously dislikes and has romantic feelings for. Regular customers include Bob Benito, the super of Becker's apartment, who is widely known as Robert.
Becker treats an HIV-positive child and is shocked to find that Reggie has in...