Dr. Aranya conducts experiments on reciprocal transplants of pituitary glands between spiders and humans in his underground labs on Zarpa Mesa, aiming to create hybrid superwomen and spiders. He invites Dr. Masterton, a renowned entomologist, to witness his creations, but Masterton is horrified and becomes the next experiment subject. The technique works better on females, and Masterton is released, only to be institutionalized. When a plane crashes on the mesa, survivors including Masterton, a wealthy financier, and his fiancée are captured to be used for further experiments.
Mesa of Lost Women
On Zarpa Mesa in Mexico, a brilliant but unhinged scientist named Arana is conducting twisted experiments in his lab, breeding giant spiders and dwarfs in a bid to create a superior breed of superwomen by infusing his female subjects with potent spider venom.