Selene, a vampire warrior, is entrenched in a conflict between vampires and werewolves, while falling in love with Michael, a human who is sought by werewolves for unknown reasons.
Picking up directly from the previous movie, vampire warrior Selene and the half werewolf Michael hunt for clues to reveal the history of their races and the war between them.
An origins story centered on the centuries-old feud between the race of aristocratic vampires and their onetime slaves, the Lycans.
When human forces discover the existence of the Vampire and Lycan clans, a war to eradicate both species commences. The vampire warrior Selene leads the battle against humankind.
In a centuries-old struggle, Selene, a deadly vampire warrior, seeks to put an end to the perpetual conflict between the Lycan clan and her own kind, who had cruelly betrayed her.